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First published online September 23, 2003

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Antimalarial compounds: from bench to bedside

Piero L. Olliaro^* and Walter R. J. Taylor

UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, World Health Organization, 20 Avenue Appia, CH-1211 Geneva 27, Switzerland

View larger version (18K): [in a new window]   Fig. 1. Parasite clearance of artesunate with sulfadoxine/pyrimethamine (AS-S/P) versus S/P alone. Although these data are from Uganda, they are representative of all the artesunate studies. The addition of artesunate increases the rate of parasite clearance.

View larger version (19K): [in a new window]   Fig. 2. Gametocyte carriage of sulfadoxine/pyrimethamine (S/P) alone and combined with one or three days of artesunate (AS). Data from Uganda.