Maintaining muscle mass during extended disuse: aestivating frogs as a model species
Nicholas J. Hudson and
Craig E. Franklin*
Physiological Ecology Laboratory, Department of Zoology and
Entomology, The University of Queensland, Brisbane, QLD 4072,
Australia

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Fig. 1. The relationship between body-mass-specific metabolic rate and percentage
muscle disuse atrophy (normalised to 12 days) for mammals with hindlimbs
artificially immobilised (r2=0.76,
P<0.01).
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Fig. 2. A schematic diagram showing factors contributing to the rate of muscle
atrophy resulting from prolonged inactivity or limb immobilisation. ROS,
reactive oxygen species.
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© The Company of Biologists Ltd 2002