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Journal of Experimental Biology 89,31-42 (1980)
Published by Company of Biologists 1980

Factors that Influence Regeneration of the Neuromuscular Junction

U. J. McMAHAN ¹, D. R. EDGINGTON ¹, and D. P. KUFFLER ¹

¹ From the Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305, U.S.A.

Regeneration of neuromuscular junctions after trauma occurs in an orderly way and relies on communication between nerve and muscle. This paper summarizes evidence that factors which direct the growth and differentiation of both pre- and postsynaptic components of regenerating neuromuscular junctions are associated with the extracellular matrix of muscles.

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