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Journal of Experimental Biology 82,139-162 (1979)
Published by Company of Biologists 1979

Respiratory, Ventilatory, and Cardiovascular Responses to Experimental Anaemia in the Starry Flounder, Platichthys Stellatus

CHRIS M. WOOD ¹, B. R. McMAHON ², and D. G. MCDONALD ¹

¹ Department of Biology, University of Calgary, Calgary, Alberta, Canada T2N 1N4; Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Bitario, Canada L8S 4K1
² Department of Biology, University of Calgary, Calgary, Alberta, Canada T2N 1N4

Unrestrained, quiescent starry flounder maintained approximately normal levels of O₂ uptake in the face of severe experimental anaemia. At haematocrits above about 5 %, the only major compensation was a reduction in venous O₂ tension which lowered venous saturation and thereby kept a constant difference between arterial and venous O₂ contents. Below a haematocrit of about 5 %, this difference decreased, and many additional compensations were invoked, including increases in ventilation, expired O₂ tension, arterial O₂ tension, and cardiac output, and decreases in systemic vascular resistance and blood pH. All changes could be reversed by restoration of haematocrit. Exercise performance and post-exercise changes in blood pH and lactate differed only slightly between anaemic and normal flounder. In wild flounder, anaemia commonly occurs and apparently only causes death at the haematocrit value (about 5 %) below which most major compensations are implemented. The respiratory strategy of the flounder during anaemia is compared with that of the rainbow trout.

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