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Journal of Experimental Biology 56,167-172 (1972)
Published by Company of Biologists 1972

Active Transport of -Aminoisobutyric Acid by the Isolated Midgut of Hyalophora Cecropia

SIGNE NEDERGAARD ¹

¹ Institute of Biological Chemistry A, University of Copenhagen, Denmark

1. The -aminoisobutyric acid flux from lumen to blood of the isolated Cecropia midgut is around 17 µmole/h, while the amino acid flux in the opposite direction is on average 0.3 µmole/h.

2. The amino acid uptake is inhibited by lack of oxygen. It is suggested that the amino acid transport from lumen to blood is an active process.

3. The amino acid uptake is inhibited by short-circuiting the midgut potential, indicating that there is no direct correlation between the active transport of potassium and the uptake of the amino acid by the midgut.

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