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Journal of Experimental Biology 55,683-694 (1971)
Published by Company of Biologists 1971

Respiratory and Circulatory Responses of Rainbow Trout Larvae to Carbon Monoxide and to Hypoxia

G. F. HOLETON ¹

¹ Department of Zoology, University of Bristol; Department of Zoology, University of Toronto, Toronto 5, Ontario

1. Larval trout undergo a transition from cutaneous respiration to gill respiration which at 10°C is well advanced by the 18th day after hatching.

2. Resting heart rate of newly hatched trout increases during the first few days, stabilizes for a while, and then drops between the 9th and 18th day after hatching. This drop may be the result of establishment of ‘vagal tone’.

3. The basic breathing response of larval trout when hypoxic is an increase in fin movements and an increase in rate and amplitude of breathing, but breathing movements slow and weaken if environmental P_O2 falls much below 40 mmHg.

4. With trout up to 8 days after hatching hypoxia causes a tachycardia. At very low P_O2 levels there is a drop in heart rate and in the amount of blood pumped by the heart. Upon restoring oxygen to very hypoxic larvae, the heart rate recovers slowly, unlike the quick abolition of bradycardia of adult fish. It appears that up to the age of 8 days from hatching, trout do not have a functional bradycardia reflex associated with hypoxia.

5. The responses of larval trout to CO and to hypoxia, and of adult trout to CO, are similar in nature. It is proposed that the basic response to anoxaemia is an increase in breathing and circulation and that the adult bradycardia response to hypoxia is a superimposed mechanism which relates circulation to the quantity of oxygen presented to the gills.

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