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The Mode of Action of the Corpus Cardiacum on the Hind Gut in Periplaneta Americana
1 Zoology Laboratory, University of Cambridge
1. Addition of a homogenate of corpora cardiaca to the fluid bathing an isolated hind gut of Periplaneta produces an increase in tonus, amplitude, frequency and co-ordination of contractions.
2. The corpus cardiacum acts by stimulating cells in the upper colon to release an indolalkylamine.
3. This amine acts on the mucles through a peripheral nervous system which can function in isolation from the central nervous system.
Submitted on March 14, 1962