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Journal of Experimental Biology 39,129-140 (1962)
Published by Company of Biologists 1962


Studies on Chitin Synthesis in the Desert Locust

D. J. CANDY 1 and B. A. KILBY 1

1 Department of Biochemistry, University of Leeds

1. In vivo studies on 5th instar and adult locusts revealed that chitin formation in thorax, abdomen, hind leg and wing was greatest during the first few days after moulting.

2. Wing extracts were used for in vitro experiments, and evidence was obtained for the presence of the following enzymes: hexokinase, phosphohexose isomerase, glutamine transaminase, phosphoglucosamine transacetylase, acetyl coenzyme-A synthetase, phosphoacetylglucosamine mutase and uridine diphosphate N-acetylglucosamine pyrophosphorylase.

3. The results are discussed, and a tentative scheme is presented for the biosynthesis of chitin in the wing of Schistocerca gregaria.

Submitted on November 7, 1961




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J. Exp. Biol.Home page
H. Merzendorfer and L. Zimoch
Chitin metabolism in insects: structure, function and regulation of chitin synthases and chitinases
J. Exp. Biol., December 15, 2003; 206(24): 4393 - 4412.
[Abstract] [Full Text] [PDF]




© The Company of Biologists Ltd 1962