spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

First published online June 11, 2007
Journal of Experimental Biology 210, 2192-2198 (2007)
Published by The Company of Biologists 2007
doi: 10.1242/jeb.02784
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Guadagnoli, J. A.
Right arrow Articles by Reiber, C. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Guadagnoli, J. A.
Right arrow Articles by Reiber, C. L.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Assessment of the pressure–volume relationship of the single ventricle of the grass shrimp, Palaemonetes pugio

J. A. Guadagnoli1,2,*, K. Tobita3 and C. L. Reiber2

1 College of Osteopathic Medicine, Touro University – Nevada, Henderson, NV 89014, USA
2 Department of Biological Sciences, University of Nevada, Las Vegas, NV, USA
3 Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA

* Author for correspondence (e-mail: jguadagnoli{at}touro.edu)

Accepted 26 March 2007

The ventricular pressure–volume (PV) relationship has been used extensively to study the mechanics and energetics in multi-chambered hearts of closed circulatory system vertebrates. In the current study we applied the use of PV loops in the assessment of cardiac mechanics and energetics in the single ventricle of a decapod crustacean possessing an open circulatory system. Anatomical differences between multi-and single-chambered hearts include multiple ostia entering and valved multiple arterial systems exiting the ventricle, and the neurogenic origin of the heartbeat in decapod crustaceans. However, the microscopic architecture and excitation–contraction coupling events are similar in both systems. Ventricular pressure and area were obtained independently and integrated into pressure–area loops. Area was then converted to volume to generate PV loops. Based on the PV loops generated in this study, the ventricle of Palaemonetes pugio processes the same primary phases of the cardiac cycle as ventricles from the multi-chambered hearts of vertebrates: (1) isovolumic contraction, (2) ventricular emptying, (3) isovolumic relaxation and (4) ventricular filling. The area enclosed by the PV loop provides a measure of stroke work and when multiplied by heart rate provides an assessment of cardiac work. This initial examination of PV loops from a single-ventricle decapod crustacean demonstrates the utility of this technique to further elucidate the cardiac mechanics and energetics of this system, and in particular during times of physiological stress.

Key words: invertebrate, cardiac function, stroke work, Palaemonetes pugio


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?




© The Company of Biologists Ltd 2007