|
| |
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
First published online November 17, 2006
Journal of Experimental Biology 209, 4591-4596 (2006)
Published by The Company of Biologists 2006
doi: 10.1242/jeb.02558
Fooling a freshwater fish: how dietary salt transforms the rainbow trout gill into a seawater gill phenotype
1 Department of Biology, Centre for Advanced Research in Environmental
Genomics, University of Ottawa, 30 Marie Curie, Ottawa, Ontario K1N 6N5,
Canada
2 CIIMAR, Rua dos Bragas 177, 4050-123 Porto, Portugal
* Author for correspondence (e-mail: sfperry{at}uottawa.ca)
Accepted 20 September 2006
Numerous fish species, including rainbow trout (Oncorhynchus mykiss), are able to inhabit both freshwater and seawater and routinely migrate between the two environments. One of the most critical adjustments allowing such successful migrations is a remodelling of the gill in which a suite of morphological and molecular changes ensure optimal function in the face of reversing requirements for salt and water balance. The remodelling leads to specific freshwater and seawater gill phenotypes that are readily identified by the orientation and/or quantities of specific ion transporters and the presence or absence of specific cell types. The proximate cues promoting gill phenotypic plasticity are unknown. Here, by assessing the consequences of a salt-enriched diet (in the absence of any changes in external salinity) in the freshwater rainbow trout, we demonstrate that internal salt loading alone, is able to induce various elements of the seawater gill phenotype. Specifically, we show upregulation of three ion transport genes, cystic fibrosis transmembrane conductance regulator (CFTR), Na+/K+/2Cl- co-transporter (NKCC1) and Na+/K+-ATPase, which are essential for ionic regulation in seawater, and the appearance of chloride cell-accessory cell complexes, which are normally restricted to fish inhabiting seawater. These data provide compelling evidence that gill remodelling during migration from freshwater to seawater may involve sensing of elevated levels of internal salt.
Key words: chloride cell, euryhalinity, osmoregulation, ionic regulation, gill, CFTR, Na+/K+-ATPase, Na+/K+/2Cl- co-transporter
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  K. R. Johnson and K. R. Olson The response of non-traditional natriuretic peptide production sites to salt and water manipulations in the rainbow trout J. Exp. Biol., September 15, 2009; 212(18): 2991 - 2997. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. R. Johnson and K. R. Olson Responses of the trout cardiac natriuretic peptide system to manipulation of salt and water balance Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2009; 296(4): R1170 - R1179. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. R. Olson and T. M. Hoagland Effects of freshwater and saltwater adaptation and dietary salt on fluid compartments, blood pressure, and venous capacitance in trout Am J Physiol Regulatory Integrative Comp Physiol, March 1, 2008; 294(3): R1061 - R1067. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Chen, T. W. Moon, K. R. Olson, R. A. Dombkowski, and S. F. Perry The effects of salt-induced hypertension on {alpha}1-adrenoreceptor expression and cardiovascular physiology in the rainbow trout (Oncorhynchus mykiss) Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2007; 293(3): R1384 - R1392. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Hiroi and S. D. McCormick Variation in salinity tolerance, gill Na+/K+-ATPase, Na+/K+/2Cl- cotransporter and mitochondria-rich cell distribution in three salmonids Salvelinus namaycush, Salvelinus fontinalis and Salmo salar J. Exp. Biol., March 15, 2007; 210(6): 1015 - 1024. [Abstract] [Full Text] [PDF]
|
|
