spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

First published online March 31, 2005
Journal of Experimental Biology 208, 1415-1419 (2005)
Published by The Company of Biologists 2005
doi: 10.1242/jeb.01547
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Panchin, Y. V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Panchin, Y. V.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Review Article

Evolution of gap junction proteins – the pannexin alternative

Yuri V. Panchin

Institute of Problems of Information Transmission, Russian Academy of Science127994 Moscow, and A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Russia

(e-mail: ypanchin{at}yahoo.com)

Accepted 7 February 2005

Gap junctions provide one of the most common forms of intercellular communication. They are composed of membrane proteins that form a channel that is permeable to ions and small molecules, connecting the cytoplasm of adjacent cells. Gap junctions serve similar functions in all multicellular animals (Metazoa). Two unrelated protein families are involved in this function; connexins, which are found only in chordates, and pannexins, which are ubiquitous and present in both chordate and invertebrate genomes. The involvement of mammalian pannexins to gap junction formation was recently confirmed. Now it is necessary to consider the role of pannexins as an alternative to connexins in vertebrate intercellular communication.

Key words: connexin, pannexin, gap junction, innexin, OPU


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Hum Mol GenetHome page
F. J. del Castillo, M. Cohen-Salmon, A. Charollais, D. Caille, P. D. Lampe, P. Chavrier, P. Meda, and C. Petit
Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins
Hum. Mol. Genet., November 11, 2009; (2009) ddp490v2.
[Abstract] [Full Text] [PDF]

Home page
 PhysiologyHome page
J. E. Cook and D. L. Becker
Gap-Junction Proteins in Retinal Development: New Roles for the "Nexus"
Physiology, August 1, 2009; 24(4): 219 - 230.
[Abstract] [Full Text] [PDF]

Home page
 J. Pharmacol. Exp. Ther.Home page
W. Ma, H. Hui, P. Pelegrin, and A. Surprenant
Pharmacological Characterization of Pannexin-1 Currents Expressed in Mammalian Cells
J. Pharmacol. Exp. Ther., February 1, 2009; 328(2): 409 - 418.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
E. Hong, F. Gurel Kazanci, and A. A. Prinz
Different Roles of Related Currents in Fast and Slow Spiking of Model Neurons From Two Phyla
J Neurophysiol, October 1, 2008; 100(4): 2048 - 2061.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
R. Iglesias, S. Locovei, A. Roque, A. P. Alberto, G. Dahl, D. C. Spray, and E. Scemes
P2X7 receptor-Pannexin1 complex: pharmacology and signaling
Am J Physiol Cell Physiol, September 1, 2008; 295(3): C752 - C760.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Bull.Home page
C. R. Magie and M. Q. Martindale
Cell-Cell Adhesion in the Cnidaria: Insights Into the Evolution of Tissue Morphogenesis
Biol. Bull., June 1, 2008; 214(3): 218 - 232.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
M. Ruiz-Meana, A. Rodriguez-Sinovas, A. Cabestrero, K. Boengler, G. Heusch, and D. Garcia-Dorado
Mitochondrial connexin43 as a new player in the pathophysiology of myocardial ischaemia-reperfusion injury
Cardiovasc Res, January 15, 2008; 77(2): 325 - 333.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
C. P.K. Lai, J. F. Bechberger, R. J. Thompson, B. A. MacVicar, R. Bruzzone, and C. C. Naus
Tumor-Suppressive Effects of Pannexin 1 in C6 Glioma Cells
Cancer Res., February 15, 2007; 67(4): 1545 - 1554.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
S. E. Von Stetina, R. M. Fox, K. L. Watkins, T. A. Starich, J. E. Shaw, and D. M. Miller III
UNC-4 represses CEH-12/HB9 to specify synaptic inputs to VA motor neurons in C. elegans
Genes & Dev., February 1, 2007; 21(3): 332 - 346.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
F. Vanden Abeele, G. Bidaux, D. Gordienko, B. Beck, Y. V. Panchin, A. V. Baranova, D. V. Ivanov, R. Skryma, and N. Prevarskaya
Functional implications of calcium permeability of the channel formed by pannexin 1
J. Cell Biol., August 14, 2006; 174(4): 535 - 546.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
C. Lehmann, H. Lechner, B. Loer, M. Knieps, S. Herrmann, M. Famulok, R. Bauer, and M. Hoch
Heteromerization of Innexin Gap Junction Proteins Regulates Epithelial Tissue Organization in Drosophila
Mol. Biol. Cell, April 1, 2006; 17(4): 1676 - 1685.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Q. Liu, B. Chen, E. Gaier, J. Joshi, and Z.-W. Wang
Low Conductance Gap Junctions Mediate Specific Electrical Coupling in Body-wall Muscle Cells of Caenorhabditis elegans
J. Biol. Chem., March 24, 2006; 281(12): 7881 - 7889.
[Abstract] [Full Text] [PDF]


© The Company of Biologists Ltd 2005