|
| |
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
First published online September 23, 2003
Review Article |
Phylogeny and cloning of ion transporters in mosquitoes
Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, USA
* Author for correspondence (e-mail: sarjeet.gill{at}ucr.edu)
Accepted 18 July 2003
Membrane transport in insect epithelia appears to be energized through proton-motive force generated by the vacuolar type proton ATPase (V-ATPase). However, secondary transport mechanisms that are coupled to V-ATPase activity have not been fully elucidated. Following a blood meal, the female mosquito regulates fluid and ion homeostasis through a series of characteristic behaviors that require brain-derived factors to regulate ion secretion. Despite the knowledge on the behaviors of the mosquito, little is known of the targets of several factors that have been implicated in cellular changes following a blood meal. This review discusses current models of membrane transport in insects and specific data on mosquito ion regulation together with the molecular aspects of membrane transport systems that are potentially linked to V-ATPase activity, which collectively determine the functioning of mosquito midgut and Malpighian tubules. Ion transport mechanisms will be discussed from a comparative physiology perspective to gain appreciation of the exquisite mechanisms of mosquito ion regulation.
Key words: V-ATPase, membrane transport, ion regulation, proton-motive force, sodium/proton exchanger, mosquito, cation-coupled chloride cotransporter
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
Related articles in JEB:
This article has been cited by other articles:
|
|
 |
|
  W. R. Harvey Voltage coupling of primary H+ V-ATPases to secondary Na+- or K+-dependent transporters J. Exp. Biol., June 1, 2009; 212(11): 1620 - 1629. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. M. Piermarini, D. Weihrauch, H. Meyer, M. Huss, and K. W. Beyenbach NHE8 is an intracellular cation/H+ exchanger in renal tubules of the yellow fever mosquito Aedes aegypti Am J Physiol Renal Physiol, April 1, 2009; 296(4): F730 - F750. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Bianchini and C. M. Wood Sodium uptake in different life stages of crustaceans: the water flea Daphnia magna Strauss J. Exp. Biol., February 15, 2008; 211(4): 539 - 547. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. R. Rheault, B. A. Okech, S. B. W. Keen, M. M. Miller, E. A. Meleshkevitch, P. J. Linser, D. Y. Boudko, and W. R. Harvey Molecular cloning, phylogeny and localization of AgNHA1: the first Na+/H+ antiporter (NHA) from a metazoan, Anopheles gambiae J. Exp. Biol., November 1, 2007; 210(21): 3848 - 3861. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Kang'ethe, K. G. Aimanova, A. K. Pullikuth, and S. S. Gill NHE8 mediates amiloride-sensitive Na+/H+ exchange across mosquito Malpighian tubules and catalyzes Na+ and K+ transport in reconstituted proteoliposomes Am J Physiol Renal Physiol, May 1, 2007; 292(5): F1501 - F1512. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. K. Pullikuth, K. Aimanova, W. Kang'ethe, H. R. Sanders, and S. S. Gill Molecular characterization of sodium/proton exchanger 3 (NHE3) from the yellow fever vector, Aedes aegypti J. Exp. Biol., September 15, 2006; 209(18): 3529 - 3544. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. P. Pollock, J. McGettigan, P. Cabrero, I. M. Maudlin, J. A. T. Dow, and S.-A. Davies Conservation of capa peptide-induced nitric oxide signalling in Diptera J. Exp. Biol., November 1, 2004; 207(23): 4135 - 4145. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. P. Ianowski and M. J. O'Donnell Basolateral ion transport mechanisms during fluid secretion by Drosophila Malpighian tubules: Na+ recycling, Na+:K+:2Cl- cotransport and Cl- conductance J. Exp. Biol., July 1, 2004; 207(15): 2599 - 2609. [Abstract] [Full Text] [PDF]
|
|
