spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Fehrenbacher, K.
Right arrow Articles by Pon, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fehrenbacher, K.
Right arrow Articles by Pon, L.
The Journal of Experimental Biology 206, 1977-1984 (2003)
doi: 10.1242/jeb.00240

Review Article

Actin comet tails, endosomes and endosymbionts

Kammy Fehrenbacher*, Thomas Huckaba*, Hyeong-Cheol Yang, Istvan Boldogh and Liza Pon{dagger}

Department of Anatomy and Cell Biology, Columbia University, New York, NY, USA
* These individuals contributed equally to this manuscript

{dagger} Author for correspondence (e-mail: lap5{at}columbia.edu)

Accepted 15 January 2003

The Arp2/3 complex consists of seven highly conserved and tightly associated subunits, two of which are the actin-related proteins Arp2 and Arp3. One of the best-studied functions of the Arp2/3 complex is to stimulate actin nucleation and force production at the leading edge of motile cells. What is now clear is that Arp2/3-complex-mediated force production drives many intracellular movements, including movement of bacterial pathogens in infected host cells, internalization of extracellular materials via phagocytosis and endocytosis, and movement of mitochondria during cell division in budding yeast. Here, we describe recent advances in the mechanisms underlying Arp2/3 complex-driven intracellular movement.

Key words: actin, cytoskeleton, endocytosis, mitochondria, organelle movement, pathogen




This article has been cited by other articles:


Home page
 GeneticsHome page
R. L. Frederick, K. Okamoto, and J. M. Shaw
Multiple Pathways Influence Mitochondrial Inheritance in Budding Yeast
Genetics, February 1, 2008; 178(2): 825 - 837.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
A. Robert, N. Smadja-Lamere, M.-C. Landry, C. Champagne, R. Petrie, N. Lamarche-Vane, H. Hosoya, and J. N. Lavoie
Adenovirus E4orf4 Hijacks Rho GTPase-dependent Actin Dynamics to Kill Cells: A Role for Endosome-associated Actin Assembly
Mol. Biol. Cell, July 1, 2006; 17(7): 3329 - 3344.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
M. Lerm, A. Holm, A. Seiron, E. Sarndahl, K.-E. Magnusson, and B. Rasmusson
Leishmania donovani Requires Functional Cdc42 and Rac1 To Prevent Phagosomal Maturation.
Infect. Immun., May 1, 2006; 74(5): 2613 - 2618.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
A. Icking, S. Matt, N. Opitz, A. Wiesenthal, W. Muller-Esterl, and K. Schilling
NOSTRIN functions as a homotrimeric adaptor protein facilitating internalization of eNOS
J. Cell Sci., November 1, 2005; 118(21): 5059 - 5069.
[Abstract] [Full Text] [PDF]

Home page
 ANN BOT (LOND)Home page
F. BALUSKA, D. VOLKMANN, and P. W. BARLOW
Eukaryotic Cells and their Cell Bodies: Cell Theory Revised
Ann. Bot., July 1, 2004; 94(1): 9 - 32.
[Abstract] [Full Text] [PDF]


© The Company of Biologists Ltd 2003