|
| |
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Review |
Going with the flow or life in the fast lane: contrasting mitochondrial responses to thermal change
1 Département de Biologie, Université Laval, Québec,
P.Q., Canada G1T 2M7, UK
2 MRC Dunn Human Nutrition Unit, Hills Road, Cambridge CB2 2XY,
UK
* e-mail: helga.guderley{at}bio.ulaval.ca
Accepted 13 May 2002
Temperature is one of the most important environmental factors affecting the physiology of animals. Seasonal fluctuations in temperature are of particular importance in aquatic ectotherms since their body temperature is in equilibrium with their environment. When an organism faces adverse environmental conditions, it can either remain active or enter into metabolic depression, adopting the strategy that maximises its fitness. Physiological responses to environmental stress occur at many different levels of organisation in an animal. Here, we focus on mitochondria, given their central importance in cellular energy metabolism. We contrast the thermal biology of skeletal muscle mitochondria from cold-active species with that of species that spend their winters in a metabolically depressed state. Specifically, we examine the modifications of mitochondrial properties during thermal/seasonal acclimation and examine mechanisms by which these modifications can arise. While compensatory responses to cold acclimation include increases in mitochondrial abundance, in the oxidative capacities of individual mitochondria and adjustments of ADP affinities, metabolic depression can reduce tissue levels of mitochondrial enzymes and mitochondrial proton leak rates.
Key words: mitochondria, seasonal temperature change, temperature compensation, metabolic depression
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
Related articles in JEB:
This article has been cited by other articles:
|
|
 |
|
  T. S Schwartz, S. Murray, and F. Seebacher Novel reptilian uncoupling proteins: molecular evolution and gene expression during cold acclimation Proc R Soc B, April 22, 2008; 275(1637): 979 - 985. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. E. Franklin, W. Davison, and F. Seebacher Antarctic fish can compensate for rising temperatures: thermal acclimation of cardiac performance in Pagothenia borchgrevinki J. Exp. Biol., September 1, 2007; 210(17): 3068 - 3074. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. D. Rogers, M. B. Thompson, and F. Seebacher Beneficial acclimation: sex specific thermal acclimation of metabolic capacity in the striped marsh frog (Limnodynastes peronii) J. Exp. Biol., August 15, 2007; 210(16): 2932 - 2938. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. B. McClelland, P. M. Craig, K. Dhekney, and S. Dipardo Temperature- and exercise-induced gene expression and metabolic enzyme changes in skeletal muscle of adult zebrafish (Danio rerio) J. Physiol., December 1, 2006; 577(2): 739 - 751. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Day and P. J. Butler The effects of acclimation to reversed seasonal temperatures on the swimming performance of adult brown trout Salmo trutta J. Exp. Biol., July 15, 2005; 208(14): 2683 - 2692. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Seebacher, W. Davison, C. J Lowe, and C. E Franklin A falsification of the thermal specialization paradigm: compensation for elevated temperatures in Antarctic fishes Biol Lett, June 22, 2005; 1(2): 151 - 154. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Seebacher, H. Guderley, R. M. Elsey, and P. L. Trosclair III Seasonal acclimatisation of muscle metabolic enzymes in a reptile (Alligator mississippiensis) J. Exp. Biol., April 1, 2003; 206(7): 1193 - 1200. [Abstract] [Full Text] [PDF]
|
|
