QUICK SEARCH:   [advanced] Author: Keyword(s):
Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents

This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Koteja, P. Articles by Garland, T. Search for Related Content PubMed PubMed Citation Articles by Koteja, P. Articles by Garland, T. Social Bookmarking                         What's this?

Journal of Experimental Biology, Vol 204, Issue 6 1177-1190, Copyright © 2001 by Company of Biologists

JOURNAL ARTICLES

Maximum cold-induced food consumption in mice selected for high locomotor activity: implications for the evolution of endotherm energy budgets

P Koteja, JG Swallow, PA Carter and T Garland
Institute of Environmental Sciences, Jagiellonian University, ul. Ingardena 6, Krakow, Poland. koteja@eko.uj.edu.pl

We studied house mice (Mus domesticus) that had been artificially selected for high activity to test the hypothesis that a high capacity for energy assimilation in cold-exposed endotherms could evolve as a correlated response to selection for increased locomotor activity. After 10 generations of selection for increased voluntary wheel-running, mice from four selected lines ran 75 % more wheel revolutions per day than did mice from four random-bred, control lines. The maximum cold-induced rates of food consumption (C(max); mean 10.6 g day(-1)) and energy assimilation (A(max); mean 141 kJ day(-1)) were not significantly higher in the selected than in the control mice. However, in cold-exposure trials, mice from the selected lines maintained body mass better than did mice from the control lines. C(max) and A(max) were positively correlated with the amount of wheel-running activity measured before cold-exposure and also with the rates of food consumption measured when the mice had access to running wheels. In females at least, the correlation was significant not only among individuals but also among adjusted means of the replicate lines, which suggests the presence of a positive genetic correlation between the traits. Thus, despite the lack of a significant difference between the selected and control lines in maximum rate of food consumption, the remaining results conform to the hypothesis that a selection for increased locomotor activity could be a factor behind the evolution of the ability to sustain activity and maintain energy balance during prolonged cold-exposure, as occurred during the evolution of mammalian and avian endothermy.
CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				L. M. Vaanholt, B. De Jong, T. Garland Jr, S. Daan, and G. H. Visser Behavioural and physiological responses to increased foraging effort in male mice J. Exp. Biol., June 1, 2007; 210(11): 2013 - 2024. [Abstract] [Full Text] [PDF]

				D. A. Syme, K. Evashuk, B. Grintuch, E. L. Rezende, and T. Garland Jr. Contractile abilities of normal and "mini" triceps surae muscles from mice (Mus domesticus) selectively bred for high voluntary wheel running J Appl Physiol, October 1, 2005; 99(4): 1308 - 1316. [Abstract] [Full Text] [PDF]