|
| |
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Journal of Experimental Biology, Vol 202, Issue 3 219-225, Copyright © 1999 by Company of Biologists
JOURNAL ARTICLES |
A Kurtz and C Wagner
Institut fur Physiologie der Universitat Regensburg, D-93040 Regensburg, Germany. armin.kurtz@vkl.uni-regensburg.de
Renin secretion at the level of renal juxtaglomerular cells appears to be controlled mainly by classic second messengers such as Ca2+, cyclic AMP and cyclic GMP, which in turn exert their effects through oppositely acting protein kinases and probably also by affecting the activity of ion channels in the plasma membrane. Thus, protein kinase A stimulates renin secretion, whilst protein kinase C and protein kinase G II inhibit renin secretion. Moreover, Cl- channels could be involved in the mediation of the inhibitory action of Ca2+ on renin secretion. This review summarizes our present knowledge about the possible actions of these kinases in renal juxtaglomerular cells and considers pathways in the organ control of renin secretion.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  Y. Yu, M. B. Lucitt, J. Stubbe, Y. Cheng, U. G. Friis, P. B. Hansen, B. L. Jensen, E. M. Smyth, and G. A. FitzGerald Prostaglandin F2{alpha} elevates blood pressure and promotes atherosclerosis PNAS, May 12, 2009; 106(19): 7985 - 7990. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Yao, T. Oite, and M. Kitamura Gap junctional intercellular communication in the juxtaglomerular apparatus Am J Physiol Renal Physiol, May 1, 2009; 296(5): F939 - F946. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Wang, E. Zolty, S. Falk, S. Summer, R. Stearman, M. Geraci, and R. Schrier Prostacyclin in endotoxemia-induced acute kidney injury: cyclooxygenase inhibition and renal prostacyclin synthase transgenic mice Am J Physiol Renal Physiol, October 1, 2007; 293(4): F1131 - F1136. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. H. Beierwaltes A different vision of the osmolar regulation of renin secretion Am J Physiol Renal Physiol, April 1, 2006; 290(4): F795 - F796. [Full Text] [PDF]
|
|
|
|
|
|
T. Takenaka, H. Okada, Y. Kanno, T. Inoue, M. Ryuzaki, H. Nakamoto, H. Kawachi, F. Shimizu, and H. Suzuki Exogenous 5'-nucleotidase improves glomerular autoregulation in Thy-1 nephritic rats Am J Physiol Renal Physiol, April 1, 2006; 290(4): F844 - F853. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Klar, H. Vitzthum, and A. Kurtz Aldosterone enhances renin gene expression in juxtaglomerular cells Am J Physiol Renal Physiol, February 1, 2004; 286(2): F349 - F355. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. B. Persson, A. Skalweit, R. Mrowka, and B.-J. Thiele Control of renin synthesis Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2003; 285(3): R491 - R497. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Yao, M. Suwa, B. Li, K. Kawamura, T. Morioka, and T. Oite ATP-Dependent Mechanism for Coordination of Intercellular Ca2+ Signaling and Renin Secretion in Rat Juxtaglomerular Cells Circ. Res., August 22, 2003; 93(4): 338 - 345. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Skalweit, A. Doller, A. Huth, T. Kahne, P. B. Persson, and B.-J. Thiele Posttranscriptional Control of Renin Synthesis: Identification of Proteins Interacting With Renin mRNA 3'-Untranslated Region Circ. Res., March 7, 2003; 92(4): 419 - 427. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. B. Persson Nitric oxide in the kidney Am J Physiol Regulatory Integrative Comp Physiol, November 1, 2002; 283(5): R1005 - R1007. [Full Text] [PDF]
|
|
|
|
 |
|
 Y. J. Chiu and I. A. Reid Effect of Sildenafil on Renin Secretion in Human Subjects Experimental Biology and Medicine, September 1, 2002; 227(8): 620 - 625. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Ito, J. Wang, J. W. Strandhoy, and J. C. Rose Importance of the Renal Nerves for Basal and Stimulated Renin mRNA Levels in Fetal and Adult Ovine Kidneys Reproductive Sciences, December 1, 2001; 8(6): 327 - 333. [Abstract] [PDF]
|
|
|
|
|
|
E. K. Jackson and R. K. Dubey Role of the extracellular cAMP-adenosine pathway in renal physiology Am J Physiol Renal Physiol, October 1, 2001; 281(4): F597 - F612. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Murthy, L. A. Haddad, N. Smith, D. Pinney, R. Tyszkowski, D. Brown, and V. Ramesh Similarities and differences in the subcellular localization of hamartin and tuberin in the kidney Am J Physiol Renal Physiol, May 1, 2000; 278(5): F737 - F746. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Wagner, M. Hinder, B. K. Kramer, and A. Kurtz Role of Renal Nerves in the Stimulation of the Renin System by Reduced Renal Arterial Pressure Hypertension, November 1, 1999; 34(5): 1101 - 1105. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Kramp, P. Fourmanoir, and N. Caron Endothelin resets renal blood flow autoregulatory efficiency during acute blockade of NO in the rat Am J Physiol Renal Physiol, December 1, 2001; 281(6): F1132 - F1140. [Abstract] [Full Text] [PDF]
|
|
