|
| |
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Journal of Experimental Biology, Vol 200, Issue 17 2363-2367, Copyright © 1997 by Company of Biologists
JOURNAL ARTICLES |
MC Quinlan, NJ Tublitz and MJ O'Donnell
Department of Biology, McMaster University, Hamilton, Ontario, Canada.
Rhodnius prolixus eliminates NaCl-rich urine at high rates following its infrequent but massive blood meals. This diuresis involves stimulation of Malpighian tubule fluid secretion by diuretic hormones released in response to distention of the abdomen during feeding. The precipitous decline in urine flow that occurs several hours after feeding has been thought until now to result from a decline in diuretic hormone release. We suggest here that insect cardioacceleratory peptide 2b (CAP2b) and cyclic GMP are part of a novel mechanism of anti-diuresis. Secretion rates of 5-hydroxytryptamine-stimulated Malpighian tubules are reduced by low doses of CAP2b or cyclic GMP. Maximal secretion rates are restored by exposing tubules to 1 mmol l-1 cyclic AMP. Levels of cyclic GMP in isolated tubules increase in response to CAP2b, consistent with a role for cyclic GMP as an intracellular second messenger. Levels of cyclic GMP in tubules also increase as urine output rates decline in vivo, suggesting a physiological role for this nucleotide in the termination of diuresis.
This article has been cited by other articles:
|
|
 |
|
  J.-P. Paluzzi, W. K. Russell, R. J. Nachman, and I. Orchard Isolation, Cloning, and Expression Mapping of a Gene Encoding an Antidiuretic Hormone and Other CAPA-Related Peptides in the Disease Vector, Rhodnius prolixus Endocrinology, September 1, 2008; 149(9): 4638 - 4646. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. A. T. Brugge, D. A. Schooley, and I. Orchard Amino acid sequence and biological activity of a calcitonin-like diuretic hormone (DH31) from Rhodnius prolixus J. Exp. Biol., February 1, 2008; 211(3): 382 - 390. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. M. Coast, R. J. Nachman, and D. A. Schooley An antidiuretic peptide (Tenmo-ADFb) with kinin-like diuretic activity on Malpighian tubules of the house cricket, Acheta domesticus (L.) J. Exp. Biol., November 15, 2007; 210(22): 3979 - 3989. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. S. Santini and J. R. Ronderos Allatotropin-like peptide released by Malpighian tubules induces hindgut activity associated with diuresis in the Chagas disease vector Triatoma infestans (Klug) J. Exp. Biol., June 1, 2007; 210(11): 1986 - 1991. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-P. Paluzzi and I. Orchard Distribution, activity and evidence for the release of an anti-diuretic peptide in the kissing bug Rhodnius prolixus J. Exp. Biol., March 1, 2006; 209(5): 907 - 915. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. P. Pollock, J. McGettigan, P. Cabrero, I. M. Maudlin, J. A. T. Dow, and S.-A. Davies Conservation of capa peptide-induced nitric oxide signalling in Diptera J. Exp. Biol., November 1, 2004; 207(23): 4135 - 4145. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. C. Massaro, L. W. Lee, A. B. Patel, D. S. Wu, M.-J. Yu, B. N. Scott, D. A. Schooley, K. M. Schegg, and K. W. Beyenbach The mechanism of action of the antidiuretic peptide Tenmo ADFa in Malpighian tubules of Aedes aegypti J. Exp. Biol., July 15, 2004; 207(16): 2877 - 2888. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. T. DOW and S. A. DAVIES Integrative Physiology and Functional Genomics of Epithelial Function in a Genetic Model Organism Physiol Rev, July 1, 2003; 83(3): 687 - 729. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. H. Hazel, J. P. Ianowski, R. J. Christensen, S. H. P. Maddrell, and M. J. O'Donnell Amino acids modulate ion transport and fluid secretion by insect Malpighian tubules J. Exp. Biol., January 1, 2003; 206(1): 79 - 91. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. J. V. Skaer, D. R. Nassel, S. H. P. Maddrell, and N. J. Tublitz Neurochemical fine tuning of a peripheral tissue: peptidergic and aminergic regulation of fluid secretion by Malpighian tubules in the tobacco hawkmoth M. sexta J. Exp. Biol., July 1, 2002; 205(13): 1869 - 1880. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
U. I. M. Wiehart, S. W. Nicolson, R. A. Eigenheer, and D. A. Schooley Antagonistic control of fluid secretion by the Malpighian tubules of Tenebrio molitor: effects of diuretic and antidiuretic peptides and their second messengers J. Exp. Biol., February 15, 2002; 205(4): 493 - 501. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. A. Eigenheer, S. W. Nicolson, K. M. Schegg, J. J. Hull, and D. A. Schooley Identification of a potent antidiuretic factor acting on beetle Malpighian tubules PNAS, December 21, 2001; (2001) 12436199. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Tanoue and T. Nishioka A Receptor-type Guanylyl Cyclase Expression Is Regulated under Circadian Clock in Peripheral Tissues of the Silk Moth. LIGHT-INDUCED SHIFTING OF THE EXPRESSION RHYTHM AND CORRELATION WITH ECLOSION J. Biol. Chem., December 7, 2001; 276(50): 46765 - 46769. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Te Brugge, S. Miksys, G. Coast, D. Schooley, and I Orchard The distribution of a CRF-like diuretic peptide in the blood-feeding bug Rhodnius prolixus J. Exp. Biol., January 8, 1999; 202(15): 2017 - 2027. [Abstract] [PDF]
|
|
|
|
|
|
R. A. Eigenheer, S. W. Nicolson, K. M. Schegg, J. J. Hull, and D. A. Schooley Identification of a potent antidiuretic factor acting on beetle Malpighian tubules PNAS, January 8, 2002; 99(1): 84 - 89. [Abstract] [Full Text] [PDF]
|
|
