|
| |
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Journal of Experimental Biology, Vol 198, Issue 3 613-627, Copyright © 1995 by Company of Biologists
JOURNAL ARTICLES |
AR Mercer, JH Hayashi and JG Hildebrand
Arizona Research Laboratories, Division of Neurobiology, University of Arizona, Tucson 85721.
The modulatory effects of 5-hydroxytryptamine (5-HT or serotonin) on voltage-gated currents in central olfactory neurones of the moth Manduca sexta have been examined in vitro using whole-cell patch-clamp recording techniques. Central olfactory neurones were dissociated from the antennal lobes of animals at stage 5 of the 18 stages of metamorphic adult development. The modulatory actions of 5-HT on voltage-activated ionic currents were examined in a subset of morphologically identifiable antennal lobe neurones maintained for 2 weeks in primary cell culture. 5-HT caused reversible reduction of both a rapidly activating A-type K+ current and a relatively slowly activating K+ current resembling a delayed rectifier-type conductance. 5-HT also reduced the magnitude of voltage-activated Ca2+ influx in these cells. The functional significance of 5-HT-modulation of central neurones is discussed.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  A. R. Mercer, P. Kloppenburg, and J. G. Hildebrand Plateau Potentials in Developing Antennal-Lobe Neurons of the Moth, Manduca sexta J Neurophysiol, April 1, 2005; 93(4): 1949 - 1958. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. C. Daly, T. A. Christensen, H. Lei, B. H. Smith, and J. G. Hildebrand Learning modulates the ensemble representations for odors in primary olfactory networks PNAS, July 13, 2004; 101(28): 10476 - 10481. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. S. Hill, K. Okada, and R. Kanzaki Visualization of modulatory effects of serotonin in the silkmoth antennal lobe J. Exp. Biol., March 2, 2003; 206(2): 345 - 352. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. R. Mercer and J. G. Hildebrand Developmental Changes in the Electrophysiological Properties and Response Characteristics of Manduca Antennal-Lobe Neurons J Neurophysiol, June 1, 2002; 87(6): 2650 - 2663. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. R. Mercer and J. G. Hildebrand Developmental Changes in the Density of Ionic Currents in Antennal-Lobe Neurons of the Sphinx Moth, Manduca sexta J Neurophysiol, June 1, 2002; 87(6): 2664 - 2675. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. S. Hill, M. Iwano, L. Gatellier, and R. Kanzaki Morphology and Physiology of the Serotonin-immunoreactive Putative Antennal Lobe Feedback Neuron in the Male Silkmoth Bombyx mori Chem Senses, June 1, 2002; 27(5): 475 - 483. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Kloppenburg, D. Ferns, and A. R. Mercer Serotonin Enhances Central Olfactory Neuron Responses to Female Sex Pheromone in the Male Sphinx Moth Manduca sexta J. Neurosci., October 1, 1999; 19(19): 8172 - 8181. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C Benkenstein, M Schmidt, and M Gewecke Voltage-activated whole-cell K+ currents in lamina cells of the desert locust schistocerca gregaria J. Exp. Biol., January 7, 1999; 202(14): 1939 - 1951. [Abstract] [PDF]
|
|
|
|
 |
|
 X. J. Sun, L. P. Tolbert, J. G. Hildebrand, and I. A. Meinertzhagen A Rapid Method for Combined Laser Scanning Confocal Microscopic and Electron Microscopic Visualization of Biocytin or Neurobiotin-labeled Neurons J. Histochem. Cytochem., February 1, 1998; 46(2): 263 - 274. [Abstract] [Full Text]
|
|
|
|
|
|
D. Sigg, C. M. Thompson, and A. R. Mercer Activity-Dependent Changes to the Brain and Behavior of the Honey Bee, Apis mellifera (L.) J. Neurosci., September 15, 1997; 17(18): 7148 - 7156. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. A. Christensen and J. G. Hildebrand Coincident Stimulation With Pheromone Components Improves Temporal Pattern Resolution in Central Olfactory Neurons J Neurophysiol, February 1, 1997; 77(2): 775 - 781. [Abstract] [Full Text] [PDF]
|
|
