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Journal of Experimental Biology, Vol 196, Issue 1 229-236, Copyright © 1994 by Company of Biologists

JOURNAL ARTICLES

Neurotransmitter transporters: three important gene families for neuronal function

GR Uhl and PS Johnson
Molecular Neurobiology Branch, NIDA, Baltimore, MD 21224.

Three distinct gene families encode transporter proteins that aid in temporal and spatial buffering of neurotransmitter and neurotransmitter metabolite concentrations and allow neurons to cycle and recycle transmitter molecules. Analyses of these gene families and their products are likely to enhance understanding of the molecular neurobiology of neuronal function and may elucidate contributors to the genetic etiologies of neurological and psychiatric disease.


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© The Company of Biologists Ltd 1994