|
| |
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Journal of Experimental Biology, Vol 172, Issue 1 335-343, Copyright © 1992 by Company of Biologists
JOURNAL ARTICLES |
H Wieczorek
Zoologisches Institut der Universitat, Munchen, Germany.
Goblet cell apical membranes in the larval midgut of Manduca sexta are the site of active and electrogenic K+ secretion. They possess a vacuolar-type ATPase which, in its immunopurified form, consists of at least nine polypeptides. cDNAs for the A and B subunits screened by monoclonal antibodies to the A subunit of the Manduca V-ATPase or by hybridisation with a cDNA probe for a plant V-ATPase B subunit have been cloned and sequenced. There is a high degree of identity to the sequences of the respective subunits of other V-ATPases. The M. sexta plasma membrane V-ATPase is an electrogenic proton pump which energizes, by the electrical component of the proton-motive force, electrogenic K+/nH+ antiport, resulting in net electrogenic K+ secretion. Since the midgut lacks a Na+/K(+)-ATPase, all solute fluxes in this epithelium seem to be energized by the V-ATPase. Thus, the midgut provides an alternative to the classical concept of animal plasma membrane energization by the Na(+)-motive force generated by the Na+/K(+)-ATPase.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  P. J. Linser, K. E. Smith, T. J. Seron, and M. Neira Oviedo Carbonic anhydrases and anion transport in mosquito midgut pH regulation J. Exp. Biol., June 1, 2009; 212(11): 1662 - 1671. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Hille and B. Walz Characterisation of neurotransmitter-induced electrolyte transport in cockroach salivary glands by intracellular Ca2+, Na+ and pH measurements in duct cells J. Exp. Biol., February 15, 2008; 211(4): 568 - 576. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. R. Rheault, B. A. Okech, S. B. W. Keen, M. M. Miller, E. A. Meleshkevitch, P. J. Linser, D. Y. Boudko, and W. R. Harvey Molecular cloning, phylogeny and localization of AgNHA1: the first Na+/H+ antiporter (NHA) from a metazoan, Anopheles gambiae J. Exp. Biol., November 1, 2007; 210(21): 3848 - 3861. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Hille and B. Walz A vacuolar-type H+-ATPase and a Na+/H+ exchanger contribute to intracellular pH regulation in cockroach salivary ducts J. Exp. Biol., April 15, 2007; 210(8): 1463 - 1471. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. K. Pullikuth, K. Aimanova, W. Kang'ethe, H. R. Sanders, and S. S. Gill Molecular characterization of sodium/proton exchanger 3 (NHE3) from the yellow fever vector, Aedes aegypti J. Exp. Biol., September 15, 2006; 209(18): 3529 - 3544. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. S. Torrie, J. C. Radford, T. D. Southall, L. Kean, A. J. Dinsmore, S. A. Davies, and J. A. T. Dow Resolution of the insect ouabain paradox PNAS, September 14, 2004; 101(37): 13689 - 13693. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. K. Pullikuth, V. Filippov, and S. S. Gill Phylogeny and cloning of ion transporters in mosquitoes J. Exp. Biol., November 1, 2003; 206(21): 3857 - 3868. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Huss, G. Ingenhorst, S. Konig, M. Gassel, S. Drose, A. Zeeck, K. Altendorf, and H. Wieczorek Concanamycin A, the Specific Inhibitor of V-ATPases, Binds to the Vo Subunit c J. Biol. Chem., October 18, 2002; 277(43): 40544 - 40548. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. DOLZER, S. KRANNICH, K. FISCHER, and M. STENGL OSCILLATIONS OF THE TRANSEPITHELIAL POTENTIAL OF MOTH OLFACTORY SENSILLA ARE INFLUENCED BY OCTOPAMINE AND SEROTONIN J. Exp. Biol., March 10, 2002; 204(16): 2781 - 2794. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. E. Giannakou and J. A. T. Dow Characterization of the Drosophila melanogaster alkali-metal/proton exchanger (NHE) gene family J. Exp. Biol., January 11, 2001; 204(21): 3703 - 3716. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Furla, D. Allemand, and M.-N. Orsenigo Involvement of H+-ATPase and carbonic anhydrase in inorganic carbon uptake for endosymbiont photosynthesis Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2000; 278(4): R870 - R881. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Beyenbach, T. Pannabecker, and W Nagel Central role of the apical membrane H+-ATPase in electrogenesis and epithelial transport in Malpighian tubules J. Exp. Biol., January 5, 2000; 203(9): 1459 - 1468. [Abstract] [PDF]
|
|
|
|
|
|
S Liao, N Audsley, and D. Schooley Antidiuretic effects of a factor in brain/corpora cardiaca/corpora allata extract on fluid reabsorption across the cryptonephric complex of Manduca sexta J. Exp. Biol., January 2, 2000; 203(3): 605 - 615. [Abstract] [PDF]
|
|
|
|
|
|
H. Merzendorfer, M. Huss, R. Schmid, W. R. Harvey, and H. Wieczorek A Novel Insect V-ATPase Subunit M9.7 Is Glycosylated Extensively J. Biol. Chem., June 11, 1999; 274(24): 17372 - 17378. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Nelson and W. R. Harvey Vacuolar and Plasma Membrane Proton-Adenosinetriphosphatases Physiol Rev, April 1, 1999; 79(2): 361 - 385. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. O'Donnell, M. R. Rheault, S. A. Davies, P. Rosay, B. J. Harvey, S. H. P. Maddrell, K. Kaiser, and J. A. T. Dow Hormonally controlled chloride movement across Drosophila tubules is via ion channels in stellate cells Am J Physiol Regulatory Integrative Comp Physiol, April 1, 1998; 274(4): R1039 - R1049. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Shahabuddin and P. F. P. Pimenta Plasmodium gallinaceum preferentially invades vesicular ATPase-expressing cells in Aedes aegypti midgut PNAS, March 31, 1998; 95(7): 3385 - 3389. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Sozen, J. D. Armstrong, M. Yang, K. Kaiser, and J. A. T. Dow Functional domains are specified to single-cell resolution in a Drosophila epithelium PNAS, May 13, 1997; 94(10): 5207 - 5212. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Davies, S. F. Goodwin, D. C. Kelly, Z. Wang, M. A. Sozen, K. Kaiser, and J. A.T. Dow Analysis and Inactivation of vha55, the Gene Encoding the Vacuolar ATPase B-subunit in Drosophila melanogaster Reveals a Larval Lethal Phenotype J. Biol. Chem., November 29, 1996; 271(48): 30677 - 30684. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Graf, W. R. Harvey, and H. Wieczorek Purification and Properties of a Cytosolic V1-ATPase J. Biol. Chem., August 23, 1996; 271(34): 20908 - 20913. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Lepier, R. Gräf, M. Azuma, H. Merzendorfer, W. R. Harvey, and H. Wieczorek The Peripheral Complex of the Tobacco Hornworm V-ATPase Contains a Novel 13-kDa Subunit G J. Biol. Chem., April 5, 1996; 271(14): 8502 - 8508. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-P. Sumner, J. A. T. Dow, F. G. P. Earley, U. Klein, D. Jäger, and H. Wieczorek Regulation of Plasma Membrane V-ATPase Activity by Dissociation of Peripheral Subunits J. Biol. Chem., March 10, 1995; 270(10): 5649 - 5653. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. J. A. Dschida and B. J. Bowman The Vacuolar ATPase: Sulfite Stabilization and the Mechanism of Nitrate Inactivation J. Biol. Chem., January 27, 1995; 270(4): 1557 - 1563. [Abstract] [Full Text] [PDF]
|
|
