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Journal of Experimental Biology, Vol 137, Issue 1 277-286, Copyright © 1988 by Company of Biologists

JOURNAL ARTICLES

Barium and calcium block Bacillus thuringiensis subspecies Kurstaki delta-endotoxin inhibition of potassium current across isolated midgut of larval Manduca sexta

DN Crawford and WR Harvey
Department of Biology, Temple University, Philadelphia, PA 19122.

Ba2+ and Ca2+ prevent and reverse the Btk delta-endotoxin inhibition of the short-circuit current in isolated lepidopteran midgut. These findings support the K+ pump-leak steady-state model for midgut K+ homeostasis and the K+ channel mechanism of Bt toxin action. They provide a new tool with which to study the interactions between Bt toxin and midgut cell membranes.


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© The Company of Biologists Ltd 1988