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Journal of Experimental Biology, Vol 115, Issue 1 191-199, Copyright © 1985 by Company of Biologists

JOURNAL ARTICLES

Differences in metabolic potential of skeletal muscle fibres and their significance for metabolic control

PD Gollnick, M Riedy, JJ Quintinskie and LA Bertocci

The role of an increase in oxidative potential of skeletal muscle in the enhanced work capacity and greater use of fat as a fuel after endurance training is discussed. Evidence is presented to illustrate that this adaptive response is probably expressed at the cellular level by a more rapid translocation into the mitochondria of the ADP generated during contractile activity. The consequence of this is a tighter control over the glycolytic process thereby creating more favourable conditions for the entry of acetyl units derived from beta-oxidation of fatty acids into the citric acid cycle.


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© The Company of Biologists Ltd 1985