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Figure 5


Fig. 5. Simulation of simultaneous changes of membrane potential and intracellular Ca2+ concentration ([Ca2+]i) for Case III of the computational model as described in Appendix 1. Membrane potential fluctuations {delta}V(t) and fluctuation ratios of intracellular Ca2+ concentration {delta}{rho}i(t) are defined as {delta}V(t){equiv}V(t)–<V(t)> and {delta}{rho}i(t){equiv}[{rho}i(t)–<{rho}i(t)>]/<{rho}i(t)>, respectively, where <V(t)> and <{rho}i(t)> are long time averages of membrane potential V(t) and intracellular Ca2+ concentration {rho}i(t), respectively. Fluctuation ratios of intracellular Ca2+ concentration {delta}{rho}i(t) are indicated as changes in [Ca2+]i in the ordinate.