Fig. 5. Simulation of simultaneous changes of membrane potential and intracellular
Ca2+ concentration ([Ca2+]i) for Case III of
the computational model as described in Appendix 1. Membrane potential
fluctuations
V(t) and fluctuation ratios of
intracellular Ca2+ concentration

i(t) are defined as
V(t)
V(t)–<V(t)>
and

i(t)
[
i(t)–<
i(t)>]/<
i(t)>,
respectively, where <V(t)> and
<
i(t)> are long time averages of membrane
potential V(t) and intracellular Ca2+
concentration
i(t), respectively. Fluctuation ratios
of intracellular Ca2+ concentration

i(t) are indicated as changes in
[Ca2+]i in the ordinate.