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Figure 9


Fig. 9. Exogenous CabTRP Ia mimics the POC activation of MCN1 and CPN2. A brief (500 ms) puff of CabTRP Ia (10–4 mol l–1) into the antero-medial aspect of the CoG neuropil excited MCN1 and CPN2 (monitored as excitatory postsynaptic potentials in GM; see text), and subsequently activated LG, GM and DG. Note that CabTRP Ia triggered pyloric-timed activity in MCN1, CPN2 and LG. Insets, showing an expanded time scale, indicate that the GM membrane potential was not pyloric-timed before CabTRP Ia application but exhibited barrages of excitatory postsynaptic potentials that were interrupted in pyloric-time after this application. Most hyperpolarized membrane potential: GM, –67 mV.