Fig. 9. Effect of colchicine on the swelling-induced changes in R_in and membrane current. The swelling-induced changes in R_in (A) and membrane current (B) were measured 5 min after reducing the extracellular osmolality (–40 mmol l^–1 NaCl), either under control conditions or after incubation of the preparations in SLS plus 25 µmol l^–1 colchicine for 1 h. After colchicine application the swelling-induced changes in R_in and membrane current were reduced. Data are means ± s.d. of N=5 experiments.