Fig. 6. Heat map summary and hierarchical clustering for components of the IGF signalling pathway during the transition from zero growth (day 0) to fast growth at 3 to 60 days (A). Rows are standardised to have a mean of 0 and s.d. of 1 so that red indicates high and green indicates low values. Regression analysis (10 fish per sample point) showing negative correlation (B) between IGF-I and IGFR1a (r²=–0.72, P=0.016), and positive correlation (C) between IGF-I and IGFBP-4 (r²=0.62, P=0.036), (D) IGF-II and IGF2R (r²=0.72, P=0.015), (E) MLC2 and IGFBP-rP1 (r²=0.93, P=0.0001) and (F) MHC and myogenin (r²=0.79, P=0.007).