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Figure 1


Fig. 1. Amino acid alignment for insulin-like growth factor binding proteins (IGFBP) 1–6. Conserved cysteine residues are indicated by a bold asterisk above the alignment. The CWCV and GCGCCXXC, RGD and heparin binding motifs are highlighted in bold text. The predicted nuclear localisation signal for IGFBP-5.1 is underlined. The asterisks below the alignment indicate completely conserved residues; :, indicates highly conserved residues;., indicates less conserved residues.