Fig. 3. Naltrindole potentiates normoxic NMDAR currents and reverses the anoxic decrease in NMDAR currents via G_i protein inhibition. Summary of changes in NMDAR currents during treatment. Data are expressed as means ± s.e.m. ^*Data significantly different from normoxic controls; data significantly different from anoxic controls; data significantly different from anoxic neurons treated with naltrindole. Significance was assessed at P<0.05. The bar indicates the duration of the treatment indicated in the key.