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Figure 3


Fig. 3. The time course of MbO2 desaturation–resaturation during apnea to eupnea cycles. The oxymyoglobin (MbO2) saturation is derived from the calibrated proximal histidyl N{delta}H signal of deoxy-Mb. MbO2 saturation is plotted against time. Breaths are indicated by marks at the base of the graph. No deoxy-Mb signal is detectable during eupnea. During apnea, the MbO2 desaturates by 20%, as calibrated from the external reference sample. Shaded area corresponds to eupnea period.