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Figure 1


Fig. 1. The molecular structures of the bile salts tested. Molecular features, designated by R1 and R2, of each bile salt tested vary at carbon positions C12 of the steroid backbone and C24 of the side-chain, respectively. The stimuli included different classes of bile salts based on the specific molecular feature (R2) attached to C24 [glycine-conjugated (GBS), taurine-conjugated (TBS), non-conjugated (NBS)]. All of the bile salts are 3{alpha}, 5β, 7{alpha} and 12{alpha} isomers. An asterisk indicates those bile salts produced by the channel catfish (Kellogg, 1975).