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Figure 2


Fig. 2. A rooted phylogenetic tree of the vertebrate Kir channel family based on the amino acid sequences. KirBac3.1 was used as an outgroup. Numbers at the nodes indicate the bootstrap values for the clade of 1000 replications. Arrowheads indicate positions of the crucian carp Kir2 proteins in the tree. Predicted inward-rectifier potassium channels of the zebrafish are indicated with an asterisk. GenBank accession numbers for the mouse (m) Kir sequences are the same as in Fig. 1B and those for zebrafish (z) are as follows: Kir1.1, NM_001045169; Kir2.1, XM_687101; Kir2.2, XM_692512; Kir2.5, XM_001335914; Kir3.2, XM_692892; Kir3.3, XM_695527; Kir4.1, XM_001342957; Kir6.1, NM_001030153; Kir6.2, NM_001039827; Kir6.3, NM_001012387; and Kir7.1, NM_001045549.