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Figure 3


Fig. 3. The effects of aging on protein levels of GABAA receptor subunit {alpha}1, β2 and {gamma}1 in the IC of FBN and F344 rats. The y-axis represents subunit protein percentage difference from young adult animals (3–4 months) of middle aged (18–20 months) and aged (28–32 months) in rat IC. Note that GABAA receptor {gamma}1 subunit protein significantly increased in aged rats of both FBN and F344. While significantly decreased {alpha}1 subunit protein was found in the IC of aged FBN rats, it was not found in aged F344 rats (*P<0.05). (Modified from Caspary et al., 1999.)