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Figure 1


Fig. 1. Amino acid alignment of trout tMEK, deduced from the determined complete coding region of the nucleotide sequence, and carp cMEK1 isoform (GenBank accession no. AB063390), human hMAP2K2 (BC018645), rat rMAP2K2 (NM_205388), and carp cMKK4 (AB063389). Specific protein interaction sites indicated are: putative MAPK docking site (amino acids 1–27; underlined), NES-sequence (AA 36–47, boxed), and catalytic domain (AA 70–364, grey background); amino acid numbering refers to trout MEK.