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Figure 3


Fig. 3. Dynamic clamp studies showing non-monotonic firing response. (A,B) Example traces from one ELL pyramidal neuron showing membrane potential (black, Vm) and injected current (gray, Im) for two different values of re (5 Hz and 20 Hz). Scale bars are the same for both A and B (40 mV, 0.4 nA, 1 s). (C) Non-monotonic firing response of ELL pyramidal neurons; normalized mean firing rate (mean ± s.d.; 16 neurons) is shown as a function of mean excitation rate, re (binned in 2 Hz increments).