Fig. 3. Time course for the stimulation of fluid secretion by supramaximal concentrations of Tenmo-ADFb (10 µmol l^–1; solid symbols and line) and Achdo-KII (1 nmol l^–1; open symbols and dotted line). Results are normalised by being expressed as a percentage of the unstimulated rate of secretion at 45 min. Data points are the means ± 1 s.e.m. of 11–12 replicates. Fluid secretion increases rapidly following addition of the individual peptides (downward arrow) and is not further elevated when they are applied together (upward arrow).