Fig. 6. (A) Effect of heat-coagulative lesioning by electric cautery on antidipsogenic effect of ANP in seawater eels (N=10 for sham-operated eels, open squares; N=10 for AP-lesioned eels, open circles; N=8 for eels with lesion outside AP, filled circles). (B) Effect of chemical lesioning by kainic acid on antidipsogenic effect of ANP in seawater eels (N=7 for sham-operated eels, open squares; N=7 for AP-lesioned eels, open circles; N=7 for eels with lesion outside AP, filled circles). The values are normalized by the averaged drinking rate for 30 min before ANP injection and expressed as percentages (mean ± s.e.m.). Inhibitory effects of ANP on drinking in AP-lesioned eels are compared with those of sham and lesion controls at each time point (^*P<0.05; ANOVA followed by Steel–Dwass test).