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Figure 1


Fig. 1. Comparison of insect NHA1 amino acid sequences. (A) Alignment of AgNHA1 with other predicted insect NHA1 amino acid sequences. Predicted transmembrane spanning domains for AgNHA1 are numbered and indicated by a red bar above the alignment. (B) A comparison of the hydropathy plots of the insect NHA1 amino acid sequences (TopPred II parameters were: GES-hydrophobicity scales; upper cut-off=1.0; lower cut-off=0.6; core window size=10; wedge window size=5; Critical loop length=60; and critical transmembrane spacer=2). Sequences were aligned relative to amino acid position (horizontal scale). Transmembrane-spanning regions predicted for AgNHA1 are indicated by the vertical red bars. Ae, Aedes aegypti; Ag, An. gambiae; Am, Apis mellifera; Ds, D. pseudoobscura; Dm, D. melanogaster; Tc, Tribolium castaneum.