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Figure 3


Fig. 3. Inhibition of G proteins after injection of GDP-ß-S. (A) Change in holding current (Im) after injection of the non-hydrolysable inhibitor of G proteins GDP-ß-S (filled circles) and of GDP (open circles) of a glial cell voltage-clamped to different holding potentials (set near to the zero current potential of each cell). (B–E) Currents during hyperpolarizing voltage (Vh) steps before and after injection of GDP-ß-S (B) or GDP (D), from which the membrane conductance (Gm) was calculated (C,E). ***P<0.001.