Fig. 2. Light microscopy and transmission electron microscopy (TEM) images of
representative normal (A,B) and sickle (C–G) cells in vitro at
pH 7.97 and 7.03–7.43, respectively. The scale bars correspond to 10
µm (A,C–F) or 200 nm (B,G). In the TEM images, n and cy indicate
nucleus and cytosol, respectively.
indicates filaments cut in
longitudinal direction, and
indicates filaments in cross section.