Fig. 7. Influence of AGR on spontaneous gastric mill rhythms. (A) Entrainment of a gastric mill rhythm with rhythmic activation of AGR. Original recordings of lgn and intracellular recording of AGR. Top: control, AGR was not stimulated. Middle: AGR was stimulated with a period of 5 s. The gastric mill rhythm was entrained to the stimulus. Bottom: stimulation of AGR with a period longer than control (8 s). The period of the rhythm corresponded to that of the stimulation. (B) Entrainment of the gastric mill rhythm. Mean of N=11 animals. The period of the rhythm is plotted over stimulation period. Both parameters are normalized to the period of the spontaneous rhythm (control). Linear regression between 0.4 and 1.6 stimulation period, R²=0.99. GMR, gastric mill rhythm. (C) Response of LG to a single burst of AGR during a spontaneous gastric mill rhythm. The AGR burst shortened the expected cycle period (phase advance). (D) Mean phase response curve of LG. AGR stimulation was capable of resetting the rhythm at any phase of the cycle. Linear regression, R²=0.95. See text for definition of abbreviations