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Figure 4


Fig. 4. Hoa-SK I and Hoa-SK II evoked increases in the frequency and amplitude of heart contractions. Both frequency and amplitude of cardiac contractions in the isolated heart increased by approximately 15% when the hearts were perfused with Hoa-SK I; frequency increased on average by 20% and amplitude by 25% when the hearts were perfused with Hoa-SK II. All changes were significantly different from 0 (two-tailed t-tests): *P<0.05; **P<0.01; N=11 preparations for Hoa-SK I, N=14 preparations for Hoa-SK II. Values are means ± s.e.m.