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Figure 6


Fig. 6. HIF-1{alpha} mRNA amounts in the liver (A), gills (B) and kidney (C) of fish exposed to hypoxia at 26°C, 18°C or 8°C. Results are shown as fold increase compared to levels in normoxic fish at 26°C and are means ± s.e.m. of 5–10 fish. Temperature has a significant effect on the hypoxia response of HIF-1{alpha} mRNA in the liver (P<0.05), gills (P<0.01) and kidney (P<0.01) of crucian carp (two-way ANOVA). Asterisks denote significant difference (P<0.05, P<0.01, P<0.01, P<0.001, P<0.01 and P<0.001 for liver 8°C 48 h, gills 26°C 6 h, gills 26°C 24 h, gills 26°C 48 h, gills 8°C 6 h and kidney 8°C 48 h, respectively) to normoxic fish at the same temperature (Holm–Sidak post test).