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Figure 4


Fig. 4. HIF-1{alpha} protein amounts in the liver (A), heart (B), gills (C), and kidney (D), of fish exposed to hypoxia at 26, 18 or 8°C. Results are shown as fold increase compared to levels in normoxic fish at 26°C and are means ± s.e.m. of 10 fish (includes variation caused by differences in fish mass). Asterisks denote significant effect of hypoxia on HIF-1{alpha} amounts (GENMOD, *P<0.01, **P<0.001, ***P<0.0001). {dagger}Significant effect of temperature on HIF-1{alpha} amounts (GENMOD, P<0.0001). GENMOD analysis does not allow post tests for testing differences between study groups.