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Figure 8


Fig. 8. Alignment and sequence comparisons between the N termini of CionaKChIP and representatives of each mammalian KChIP isoform. (A) Alignment between the N termini of CionaKChIP and KChIP4a (GenPept. accession number AAL86766), which contains the K inactivation suppressor domain (KIS). (B) Alignment between the N termini of CionaKChIP and KChIP1a (GenPept. accession number AAL12489). (C) Alignment between the N termini of CionaKChIP and KChIP2a (GenPept. accession number AAF81755). (D) Alignment between the N termini of CionaKChIP and KChIP3a (GenPept. accession number Q9Y2W7). T-Coffee software (Notredame et al., 2000) was used to align these sequences. Residues that are identical for each pair of sequences are boxed.