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Figure 5


Fig. 5. INa under action potential clamp. Representative atrial and ventricular action potentials (top) were used to elicit tetrodotoxin-sensitive INa (middle) at physiological external Na+ concentration (154 mmol l-1). The bottom panel shows Vmax mean (± s.e.m.; N=12) calculated from INa, Vmax measured in the intact tissue and their difference. Asterisks show a significant difference (P<0.05) between atrial and ventricular myocytes.