Fig. 5. Responses of large and small spiking neurons during cross-adaptation experiments. (A) Typical adapted response to two 0.5 s stimuli of E12-14:OAc (10 µg) with an interval of 0.2 s, indicated as horizontal bars. (B) Histograms showing number of spikes per 0.1 s (means + s.e.m.) of large and small spiking neurons (large and small) in sensillum type 1 (N=5) before and after adaptation. Two stimuli [E12-14:OAc (E12) and Z12-14:OAc (Z12) in different stimulus combinations] (10 µg) were presented successively. Note how the activity of the second stimulation is equally affected by prestimulation of both the same and the opposite isomer.