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Figure 2


Fig. 2. Inhibition of dopamine uptake by cocaine in isolated snail brains measured by HPLC. Cocaine doses ranging from 0.03-10.0 µmol l-1 were used, and dopamine uptake is reported as mean ± s.e.m. of dopamine levels remaining outside the tissue (N=6 for controls; N=3 for 0.03 µmol l-1; N=4 for all other doses). The IC50 for cocaine was estimated to be approximately 0.03 µmol l-1.