Fig. 5. Phalloidin-labeled saccular epithelia showing evidence of hair bundle loss following exposure to noise. (A) Control tissue from the caudal end of the saccule showing normal complement of hair bundles. (B) The same region of the saccule in an animal following 48 h of noise exposure and 1 day of recovery. (C) High magnification image of the saccule in B showing a scar formation characteristic of hair cell loss (arrow) and a bundleless cuticular plate (arrowhead). Scale bars, (A,B) 20 µm, (C) 5 µm.