Fig. 3. Changes in gluconeogenic enzyme specific activities (i.u. mg^-1 protein) in liver of Fundulus grandis held under normal and reduced oxygen levels for 4 weeks at 27°C. The y axis represents the percent change in the mean value for each enzyme measured from hypoxic fish relative to the normoxic value. Asterisks indicate significant differences between mean specific activity values from normoxic and hypoxic groups (^*P0.05; ^**P0.001; see Table 3). MDH, malate dehydrogenase; PEPCK, phosphoenolpyruvate carboxykinase; FBPase, fructose-1,6-bisphosphatase; G6Pase, glucose-6-phosphatase.