Fig. 6. The effect of increasing the rate of mitochondrial ATP production and myosin ATPase activity during steady-state contraction in small fibers on the temporal and spatial profiles of AP (A,C,E) and ATP (B,D,F). Metabolite concentrations during a typical steady-state contraction, where V_m,mito=1.00x10^-14 mmol µm^-2 s^-1 and V_m,myo=1 mmol l^-1 s^-1 (A,B), during steady-state with a threefold increase in V_m,mito and V_m,myo (C,D), and during steady-state with a sevenfold increase in V_m,mito and V_m,myo (E,F).